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Senior Research Associate: Histology
- Permanent
- Biological Sciences
- United States
Senior Research Associate - Permanent - San Francisco, CA
Passionate about transforming tissue into breakthrough insights? Step into a role where your histology expertise drives real drug discovery impact.
We are seeking a Senior Research Associate to join our client's dynamic team in CA, US.
Primary Responsibilities:
The successful candidate will support research projects by performing histological procedures, including tissue preparation, sectioning, standard staining, immunostaining, imaging, and image quantification.
Skills & Requirements:
- MS in Biology or a similar discipline with at least 4 years of industry experience, or a BA/BS with 6 years of relevant experience demonstrating direct participation in drug discovery efforts by IHC and other tissue-based techniques
- ASCP certification (HT or HTL) is desirable
- Experience in performing, optimizing, and implementing qualitative and quantitative tissue-based methodologies, ranging from tissue handling and processing, sectioning with microtome or cryostat, and histochemical staining, is required
- Experience with standard and advanced microscopy and digital pathology is required
- Proficient at employing whole-slide automated image analysis (e.g., HALO and Definiens) and analyzing large data sets using statistical and data visualization programs (e.g., Prism, Spotfire) to quantify tissue-based efficacy markers is preferred
- Understanding of mouse and human comparative microscopic anatomy, characterization of transgenic animals
- Familiar with the analysis and interpretation of data generated from tissue-based target expression studies, with statistical approaches, and successful presentation of pathology
The Senior Research Associate's responsibilities will be:
- Preparation of tissue, including grossing and embedding
- Sectioning tissue using various equipment, including cryostat, microtome, vibratome, and sliding-frozen microtome
- High volume automated and manual Immunostaining
- Experience with chromogenic and fluorescence immunodetection (single and multiplex)
- Experience with automatic slide stainers such as Leica Bond Rx and Biocare IntelliPATH FLX is a plus
- Manual and automatic cover-slipping
- Experience with high-throughput slide scanners such as Hamamatsu Nanozoomer and Zeiss Axioscan is a plus
- Capturing images with fluorescence and brightfield microscopy
- Carry out histological staining such as H&E, nuclear counterstaining, and other standard histological stains
- Design and troubleshoot experiments, analyze data, and present in meetings with guidance from senior staff
- Use of a microscope to examine the quality of staining, perform standard microscopic tasks, view samples, and produce high-quality images
- Work with CRO for the outsourcing of tissue embedding and sectioning, when necessary
Compensation:
- $120 000 - $140 000 Per Annum
If you are having difficulty in applying or if you have any questions, please contact Shannon Briggs at s.briggs@proclinical.com.
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.
探花合集 is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. 探花合集 is acting as an Employment Agency in relation to this vacancy.
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